课程名称︰讯息传递与疾病
课程性质︰选修
课程教师︰主授陈青周（此范围为陈青周/李建国/蔡丰乔老师授课）
开课学院：医学院
开课系所︰医卫共同课程
考试日期（年月日）︰2017/06/09
考试时限（分钟）：110分钟
试题 :
(以下叙述均非与原题目完全相同，仅就考试主题作最接近之题目描述)
陈青周老师part：占45分
(范围：NF-κB and Ubiquitination; Epigenetic mechanisms;
Targeting transduction pathways for research and medical intervention)
问答题：
1. Please describe two examples of epigenetic drugs. Detail their functions
and the mechanisms. (10%)
2. What is bivalent histone methylation? (5%)
3. Describe the process of ubiquitination: use IκBα as example. (15%)
4. Targeting growth factor signaling pathway, choose one example of monoclonal
antibody drug and one example of small drug and detail their modes of
actions. (15%)