这问题很帅....
主要就是Steam上的Skyrim SE 更新了 1.5.16版本，结果使得 SKSE64 2.0.4不能用了，因
为版本太新。
SSKSE64 2.0.4版的版号是对应 Skyrim SE 1.5.3版的。
我查了一下才找到国外有人找出解决方法。
https://forums.nexusmods.com/index.php?/topic/6140428-skse64-fix/
SKSE64 FIX
Spread these steps! That's how you solve this nonsense. Show them!
1. Start by pressing win+R, and then pasting: steam://nav/console
按 win + R 叫出执行视窗，执行 steam://nav/console，叫出 steam console。
2. A steam console should appear now, just paste the following line:
download_depot 489830 489833 911281757511576655
在 steam console 中输入指令 download_depot 489830 489833 911281757511576655
3. The v1.5.3 exe will downloaded to
[...]steamapps/content/app_489830/depot_489833
steam会下载 SkyrimSE 执行档 1.5.3版 到：
C:\Steam\steamapps\content\app_489830\depot_489833
(当然每个人steam装的目录会不同)
4. Just go to where the exe was downloaded and paste the old exe inside your
root skyrim folder replacing the "new" one.
把 SkyrimSE 1.5.3版 复制贴上到你的 SkyrimSE 根目录下取代 1.5.16版。
SKSE64 2.0.4 就能用了。