Tulane study shows COVID-19’s lingering impacts on the brain
April 01, 2022
COVID-19 patients commonly report having headaches, confusion and other
neurological symptoms, but doctors don’t fully understand how the disease
targets the brain during infection.
covid 确诊病患常有头痛和其他神经系统症状 但目前不完全了解病毒如何影响脑部
researchers at Tulane University have shown in detail how COVID-19 affects the
central nervous system, according to a new study published in Nature
Communications. The findings are the first comprehensive assessment of
neuropathology associated with SARS-CoV-2 infection in a nonhuman primate
model.
杜兰大学研究人员展示 病毒影响中枢神经系统
这是首次在非人类灵长类 对 covid 病毒的神经病理学研究
发表在 Nature Communications 自然通讯期刊
The research team found severe brain inflammation and injury consistent with
reduced blood flow or oxygen to the brain, including neuron damage and death.
Microhemorrhages, or small bleeds in the brain, were also present.
发现严重的脑部发炎 往脑部血流量及氧气输送减少 包含神经元损伤和死亡
还有脑部的微量或少量出血
Surprisingly, these findings were seen in subjects that did not experience
severe respiratory disease from the virus.
惊讶的是 这些症状在没有严重呼吸道疾病的感染个体也有出现
“Because the subjects didn’t experience significant respiratory symptoms, no
one expected them to have the severity of disease that we found in the brain,
” Fischer said. “But the findings were distinct and profound, and undeniably
a result of the infection.”
感染个体没有明显呼吸道症状 没人预期脑部会有严重疾病
但这些发现是独特的 不可否认是感染造成的
The findings are also consistent with autopsy studies of people who have died
of COVID-19, suggesting that nonhuman primates may serve as an appropriate
model, or proxy, for how humans experience the disease.
这些发现也与 covid 感染死亡的人类验尸结果一致
显示非人类灵长类可替代人类做为研究疾病模型
Neurological complications are often among the first symptoms of SARS-CoV-2
infection and can be the most severe and persistent. They also affect people
indiscriminately — all ages, with and without comorbidities, and with varying
degrees of disease severity.
神经系统症状经常是第一个 covid 感染症状 而且可能是最严重及持久的
而且它不挑人 年龄 有无共病症 轻重症 都有机会
Fischer hopes that this and future studies that investigate how SARS-CoV-2
affects the brain will contribute to the understanding and treatment of
patients suffering from the neurological consequences of COVID-19 and long
COVID.
Fischer 希望这项 covid 如何影响大脑的研究
对治疗 covid 或 long covid 的神经系统疾病患者有帮助
来源：
https://news.tulane.edu/pr/tulane-study-shows-covid-19s-lingering-impacts-
brain
缩：
https://reurl.cc/pWzWKQ
论文：
https://www.nature.com/articles/s41467-022-29440-z