塔绿班不敢面对的真相就是，高端自己在文章提到自己没有保护力资料，只能说自己中和
抗体很多（跟之前大家就已经知道的故事差在哪？）
然后，高端自己也提到，自己是在中和抗体最高的时间点取血清（跟爱刷存在感的某前版
主一样），但血清之后变低还有没有保护效果不知道，因为牵扯到t细胞的免疫反应，无
法得知。（也就跟大家说的一样，没有保护力资料，根本是假的）
不过塔绿班还是高潮的很爽啦！嘻嘻
A limitation of our study is that the sera were taken 4 weeks after the second
shot of MVC-COV1901 when immunity has peaked and only just started to wane. T
herefore, we could not evaluate the impact of waning immunity on the neutraliz
ing capacity against the variants. The study cannot evaluate the role of T-cel
l responses elicited by the vaccine as it was reported that the T-cell respons
es to immunization may confer heterotypic coverage and are less affected by Vo
Cs [31].
COVID-19 vaccines in phase 3 clinical trials in South Africa when the Beta var
iant became predominant showed considerably high protection against severe cli
nical endpoints, while overall efficacy is lower than at sites outside of Sout
h Africa [32].
Since there are no correlates of protection being published for emerging varia
nts, it warrants further study on how the reduced neutralizing titers will tra
nslate to clinical endpoints. We are currently conducting a randomized, double
-blind, placebo-controlled phase 2 study for safety and immunogenicity of MVC-
COV1901 with >3800 subjects (NCT04695652). The samples from the phase 2 trial
would allow us to further investigate the effects of variants on neutralizing
titers by using a larger set of samples and newer variants.