家母于5年前罹患乳癌(左乳)，当时为第一期。
后续经化疗6次，放疗等，去年8月还欢庆终于抗癌成功。
没想到前几天于定期检验(2/19)时，医生触诊又摸到疑似肿瘤的怪东西。
这次为右乳。
立即由医生安排进行粗针穿刺(2/20)。
于刚刚(2/23)查询健保快易通的报告如下
The specimen submitted consists of six tissue fragments measuring up to
0.8x0.1x0.1 cm in size, fixed in formalin. Grossly, they are yellow and
elastic. All for one section and labeled as A1;Microscopically, the breast
shows neoplastic tumor cells with hyperchromasia, nuclear pleomorphism and
brisk mitotic figures arranged in solid nested pattern.
Immunohistochemically, the tumor cells show E-cadherin(+) and CK5/6(-).
Immunostain of p63 shows preserved myoepithelial cells around the tumor
nests. Taken together, high grade ductal carcinoma in situ is diagnosed. The
pathologic diagnosis has been discussed and confirmed by Peer Slide Review.
Immunohistochemical Study * ER: Negative (0%) [Leica Biosystems Estrogen
Receptor (Clone 6F11) mouse monoclonal antibody] * PR: Positive (35%, weak to
moderate) [Leica Biosystems Progesterone Receptor (Clone 16) mouse monoclonal
antibody
我想问3个问题
1. 如果我没有理解错误的话，家母应为DCIS，0期的原位癌。
0期原位癌，到底是癌症吗? 为何又说有检验到癌细胞?
2. 0期原位癌，有分等级吗?这边看到的是high grade
应该可以理解为比较不好的原位癌吗?
3. 5年前，家母乳癌一期时，可以看到ER、PR、Her2以及ki67等数值。
但这次的报告，仅有看到ER为negtive、PR为弱到中阳性。
没有看到Her2以及ki67的数值。
是否因为是原位癌，就没有这些数值?
以上3个问题，可能再麻烦大家可以一起讨论吗?
感激不尽。