感谢 yevvi 大提供开放年代以前的数据，在此补上
(请容许我借用大大的上色习惯)
澳网
1908 Fred Alexander (USA) def. Alfred Dunlop (AUS)
3-6 3-6 6-0 6-2 6-3
1960 Rod Laver (AUS) def. Neale Fraser (AUS)
5-7 3-6 6-3 8-6 8-6
1965 Roy Emerson (AUS) def. Fred Stolle (AUS)
7-9 2-6 6-4 7-5 6-1
法网
1909 Max Decugis (FRA) def. Maurice Germot (FRA)
3-6 2-6 6-4 6-4 6-4
1946 Marcel Bernard (FRA) def. Jaroslav Drobny (TCH)
3-6 2-6 6-1 6-4 6-3
1962 Rod Laver (AUS) def. Roy Emerson (AUS)
3-6 2-6 6-3 9-7 6-2
温网
1895 Wilfried Braddeley (BRI) def. Wilberforce Eaves (BRI)
4-6 2-6 8-6 6-2 6-3
1899 Reginald Doherty (BRI) def. Arthur Gore (BRI)
1-6 4-6 6-3 6-3 6-3
1909 Arthur Gore (BRI) def. Major Ritchie (BRI)
6-8 1-6 6-2 6-2 6-2
1921 Bill Tilden (USA) def. Brian Norton (SAF)
4-6 2-6 6-1 6-0 7-5
1927 Henri Cochet (FRA) def. Jean Borotra (FRA)
4-6 4-6 6-3 6-4 7-5
美网
1912 Maurice McLoughlin (USA) def. Wallace Johnson (USA)
3-6 2-6 6-2 6-4 6-2
1922 Bill Tilden (USA) def. Bill Johnson (USA)
4-6 3-6 6-2 6-3 6-4
1940 Don McNeill (USA) def. Bobby Riggs (USA)
4-6 6-8 6-3 6-3 7-5
1947 Jack Kramer (USA) def. Frank Parker (USA)
4-6 2-6 6-1 6-0 6-3
1949 Pancho Gonzales (USA) def. Ted Schroeder (USA)
16-18 2-6 6-1 6-2 6-4
注：Pancho Gonzales 是 Andre Agassi 姐夫，1995年过世。
以下是开放年代之后，从 ATP 官网看来的：
法网
1974 Bjorn Borg (SWE) def. Manuel Orantes (ESP)
2-6 6-7(1) 6-0 6-1 6-1
1984 Ivan Lendl (CZE) def. John McEnroe (USA)
3-6 2-6 6-4 7-5 7-5
1999 Andre Agassi (USA) def. Andriy Medvedev (UKR)
1-6 2-6 6-4 6-3 6-4
2004 Gaston Gaudio (ARG) def. Guillermo Coria (ARG)
0-6 3-6 6-4 6-1 8-6 (saved 2 mp at 5-6 in the fifth set)
美网
2020 Dominic Thiem (AUT) Alexander Zverev (GER)
2-6 4-6 6-4 6-3 7-6(6)
注：
1. Orantes 是 1975 美网冠军 (当年美网是绿土)，36 座单打冠军有 31 座是红土
2. 1984 的 McEnroe 82 胜 3 负，单一赛季最高胜率
3. Agassi 完成生涯大满贯
4. 就是新闻一直提到的：上一个八强名单没有 Big3 身影的大满贯赛