[新闻] 加拿大罕见的狂犬病致死案例引发学界重视

楼主: STAV72 (刁民党党务主委)   2026-06-29 17:00:23
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1.媒体来源:
外媒 MedicalXpress
2.记者署名:
edited by Gaby Clark, reviewed by Robert Egan
由加比·克拉克 编辑 ,罗伯特·伊根审阅
3.完整新闻标题:
Fatal rabies case with no visible wound shows why bat contact alone should
trigger immediate vaccination, experts say
专家称,一例无明显伤口的致命狂犬病病例表明,仅接触蝙蝠就应立即接种疫苗。
4.完整新闻内文:
Fatal rabies case with no visible wound shows why bat contact alone should
trigger immediate vaccination, experts say
by Canadian Medical Association Journal
edited by Gaby Clark, reviewed by Robert Egan
Ontario's first fatal rabies case since 1967 provides critical guidance to
help prevent deaths from rabies in future cases. The article was published in
the Canadian Medical Association Journal.
专家称,一例无明显伤口的致命狂犬病病例表明,仅接触蝙蝠就应立即接种疫苗。
加拿大医学会杂志
由加比·克拉克 编辑 ,罗伯特·伊根审阅
安大略省自1967年以来首例狂犬病死亡病例为预防未来狂犬病死亡提供了重要指引。该文
章发表于《加拿大医学会杂志》。
Human rabies is caused by a virus and is almost always fatal, but
post-exposure prophylaxis (PEP), with a series of rabies vaccines and human
rabies immune globulin injections, can prevent death if given promptly and
before symptoms develop. In North America, bats, raccoons, skunks and foxes
are the main carriers of rabies. Bats are the most common cause of rabies and
pose a heightened risk because scratches or bites may be small and hard to
see.
This fatal rabies case occurred in an 11-year-old boy who awoke with a bat
lying on his mouth and nose and had no apparent bite or scratch marks.
Nineteen days after exposure, he went to an emergency department with a range
of symptoms, including vomiting, facial "pins and needles" and numbness, and
was later diagnosed with rabies. The health care team provided supportive
care, as there is no cure once rabies symptoms develop.
The parents agreed to share their son's case to help raise awareness of
rabies.
人类狂犬病由病毒引起,几乎总是致命的,但如果在症状出现前及时进行暴露后预防(
PEP),包括接种一系列狂犬病疫苗和注射人狂犬病免疫球蛋白,则可以避免死亡。在北
美,蝙蝠、浣熊、臭鼬和狐狸是狂犬病的主要携带者。蝙蝠是狂犬病最常见的传播媒介,
由于其造成的抓伤或咬伤可能很小且难以发现,因此风险更高。
这例致命的狂犬病病例发生在一名11岁男孩身上。他醒来时发现一只蝙蝠趴在他的口鼻上
,身上没有明显的咬伤或抓痕。接触狂犬病毒19天后,他因呕吐、脸部麻木和刺痛等一系
列症状前往急诊室就诊,后被确诊为狂犬病。由于狂犬病一旦出现症状便无法治愈,医疗
团队只能提供支持性治疗。
这对父母同意分享他们儿子的病例,以帮助提高人们对狂犬病的认识。
"Any direct human contact with a bat, even in the absence of a visible bite
or scratch, is an indication for PEP and should be discussed with public
health authorities," writes Dr. Brian Hummel, a pediatric infectious disease
specialist at McMaster Children's Hospital and assistant professor at
McMaster University, Hamilton, Ontario, with co-authors.
"This is especially important to consider as we approach the summer months,
when human–bat encounters are at their peak," Hummel emphasizes.
People who may have been in contact with a wild animal that could potentially
have rabies should seek medical attention promptly. In cases of possible
rabies virus exposure, public health authorities should be notified and PEP
started in consultation.
“即使没有明显的咬伤或抓伤,任何人与蝙蝠的直接接触都是进行暴露后预防的指征,应
该与公共卫生部门讨论,”麦克马斯特儿童医院儿科传染病专家、麦克马斯特大学助理教
授布莱恩·胡梅尔博士及其合作者写道。
“随着夏季临近,人与蝙蝠相遇的几率达到高峰,这一点尤其值得考虑,”胡梅尔强调。
可能接触过携带狂犬病毒的野生动物的人员应立即就医。如怀疑接触过狂犬病毒,应通知
公共卫生部门,并咨询相关专家后开始进行暴露后预防(PEP)。
Although rabies in humans is rare, with only 28 cases reported since 1924,
the authors recommend awareness, prompt action with PEP and clinical judgment
in cases of suspected exposure to the rabies virus.
"Rabies is almost always fatal, with no established efficacious therapies,
making prevention crucial. Rabies PEP is highly effective if administered
promptly, in consultation with public health authorities, after any direct
human contact with a bat, even in the absence of visible lesions. Bats may or
may not show classic signs of rabies; hence, any direct human contact with a
bat is considered high risk," the authors conclude.
In people with neurological symptoms that may be compatible with rabies,
clinicians should ask about exposure to potentially rabid animals.
虽然人类狂犬病很少见,自 1924 年以来仅报告了 28 例,但作者建议提高警惕,在疑似
接触狂犬病毒的情况下迅速采取暴露后预防措施,并进行临床判断。
“狂犬病几乎总是致命的,目前尚无有效的治疗方法,因此预防至关重要。如果在与蝙蝠
直接接触后,即使没有可见的病变,也应立即在公共卫生部门的指导下进行狂犬病暴露后
预防,那么狂犬病暴露后预防非常有效。蝙蝠可能表现出也可能不表现出狂犬病的典型症
状;因此,任何与蝙蝠的直接接触都被认为是高道风险的总结。
对于出现可能与狂犬病相符的神经系统症状的人,临床医生应询问是否接触过可能患有狂
犬病的动物。
5.完整新闻连结 (或短网址)不可用YAHOO、LINE、MSN等转载媒体:
https://medicalxpress.com/news/2026-06-fatal-rabies-case-visible-wound.html
6.备注:
当狂犬病不用咬伤直接皮屑排遗接触传染满要命的,该案例潜伏期两个礼拜后轻微厌食
,不到两个月就死。
https://www.cmaj.ca/content/198/25/E969
患者住院期间病情复杂,出现自主神经功能障碍、呼吸器相关性肺炎及进行性神经功能恶
化。入院第5天,脑干反射消失。入院第17天,停止维生治疗,患者在家人的陪伴下安详
离世。
狂犬病潜伏期通常为1-2月,但时间变化大,在记录中曾出现4天到数年不等,但目前WHO
认定的狂犬病的潜伏期不超过1年。

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