Xyzal During Pregnancy and Breastfeeding
Byr. Amos Grunebaum, MD
Updated on March 25, 2019
eneric Name: Levocetirizine
Indications: Antihistamine prescribed for perennial (year-round) allergies, seasonal allergies and skin-related symptoms of allergies, including hives and itching. May be prescribed off-label for other conditions.FDA Drug Category: B
Summary Recommendations: Xyzal is prescribed to patients with year-round or seasonal allergies. Thisllergy medicationan be prescribed to patients as young as six months old, in the case of year-round allergies. There are no reports of negative side effects in pregnant women or fetuses, thus theregnancy drug category B.
General Precautions: Patients with a known allergy to Zyrtec (cetirizine), drugs containing levocetirizine or cetirizine should not take Xyzal. Xyzal is contraindicated in patients with end-stage kidney disease and/or patients on dialysis. Patients with any stage of kidney disease or liver disease should consult a physician about possible side effects before taking Xyzal.
Children absorb twice the amount of Xyzal as adults so proper dosing is imperative for child-safety. Never give a child more than the prescribed dose of Xyzal. If allergy symptoms do not improve or if a fever develops, contact your physician immediately.
Symptoms reported in patients taking Xyzal include fatigue, weakness, dry mouth and weight gain. More serious, but less frequently reported, symptoms include hearing problems, nosebleeds, difficulty urinating and agitation. If you feel you are experiencing serious side effects contact your physician.
Effects Whilerying to Conceive: Animal studies delivered doses 25 times higher than therapeutic doses in humans with no negative effect on male or female fertility.
Effects on Pregnancy: Xyzal is in therug category B, according to the FDA. Doses in excess of 320 times that prescribed to humans showed no negative effects,regnancy complicationsr fetal complications. Human studies on the effect of Xyzal during pregnancy have not been completed. As is the case with all prescription and over-the-counter medication, Xyzal should only be used during pregnancy when absolutely necessary. Discuss any concerns about taking the drug during pregnancy with your doctor.
Safe During Breastfeeding: There are no reports of negative side effects in infants at small doses of Xyzal. Larger doses may be associated with infant drowsiness or lethargy. There are also reports of reduced milk supply in women taking larger doses of Xyzal. About 10% of mothers interviewed reported infant irritability after breastfeeding. Another 1.6% reported infant lethargy.
哺乳中母亲小剂量的使用没有造成婴儿副作用的报告，较高的使用剂量可能造成婴儿嗜睡。在访谈中，约有百分之十的妈妈表示婴儿哺乳后有些躁动，另有百分之1.6的妈妈表示婴儿比较缺乏活力。另外也可能造成哺乳的妈妈奶量分泌减少。
Antihistamines may reduceerum prolactin levels. This could affectilk production, leaving thereastfeedingmother with diminishedilk supplieswhen taking drugs like Xyzal.
※ 引述《bunny0402 (Bunny)》之铭言：
: 生完大宝一年多之后
: 莫名其妙全身痒但没疹子
: 看诊才发现已经是慢性荨麻疹
: 过了两年都无法停药
: 现在都是每晚一颗“驱异乐”
: 因为怀孕的关系有询问过医生用药安全的问题
: 医生说怀孕没什么影响
: 但是免疫科医生说这个药不能喂母奶！
: 可能要换别的药或直接类固醇T_T
: 产检的时候也再询问妇产科医生
: 他看了一下我的药名后
: 跟我说可以吃啦没问题！
: ㄜ......我脑问号不知道该听谁的说法
: 我还问医生说搞不好我生完体质又变了
: 病也许就好了也说不定耶
: 医生直接回我不要想太多了
: 呜呜呜呜呜
: 有没有也是慢性荨麻疹的妈咪
: 在哺乳期间有用驱异乐
: 或是有换成哪一种药是同样效果的呢？
: 想参考参考
: 先谢谢大家了！