总计有11位亚洲球员以排名直接进入女单会内赛，会外赛晋级两位共13位。
大坂直美列第二种子，Rybakina第21种子。
首轮王蔷将遭遇谢淑薇，是唯一一组亚洲对战，也是亚洲球员必定能晋级次轮的保证。
BARTY Ashleigh AUS [1] vs PERA Bernarda USA
LINETTE Magda POL vs PAQUET Chloé FRA (W)
QUALIFIER (Q) vs SHARMA Astra AUS (W)
PUTINTSEVA Yulia KAZ vs JABEUR Ons TUN [25]
GAUFF Coco USA [24] vs QUALIFIER (Q)
王蔷 WANG Qiang CHN vs 谢淑薇 HSIEH Su-Wei TPE
梁恩硕 LIANG En-Shuo TPE (Q) vs FERRO Fiona FRA
SEVASTOVA Anastasija LAT vs BRADY Jennifer USA [13]
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PLISKOVA Karolina CZE [9] vs VEKIC Donna CRO
SUAREZ NAVARRO Carla ESP vs STEPHENS Sloane USA
LEPCHENKO Varvara USA (Q) vs 张帅 ZHANG Shuai CHN
PETKOVIC Andrea GER vs MUCHOVA Karolina CZE [18]
ALEXANDROVA Ekaterina RUS [32] vs WILLIAMS Venus USA
KREJCIKOVA Barbora CZE vs PLISKOVA Kristyna CZE
LI Ann USA vs GASPARYAN Margarita RUS
BABEL Oceane FRA (W) vs SVITOLINA Elina UKR [5]
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KENIN Sofia USA [4] vs OSTAPENKO Jelena LAT
QUALIFIER (Q) vs BLINKOVA Anna RUS
MARTINCOVA Tereza CZE vs JOROVIC Ivana SRB
朱琳 ZHU Lin CHN vs PEGULA Jessica USA [28]
SAKKARI Maria GRE [17] vs QUALIFIER (Q)
PAOLINI Jasmine ITA vs QUALIFIER (Q)
WATSON Heather GBR vs DIYAS Zarina KAZ
QUALIFIER (Q) vs MERTENS Elise BEL [14]
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MUGURUZA Garbine ESP [12] vs KOSTYUK Marta UKR
郑赛赛 ZHENG Saisai CHN vs SORRIBES TORMO Sara ESP
QUALIFIER (Q) vs GRACHEVA Varvara RUS
GIORGI Camila ITA vs MARTIC Petra CRO [22]
KONTAVEIT Anett EST [30] vs GOLUBIC Viktorija SUI
QUALIFIER (Q) vs MLADENOVIC Kristina FRA
PETERSON Rebecca SWE vs ROGERS Shelby USA
JUVAN Kaja SLO vs SWIATEK Iga POL [8]
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WILLIAMS Serena USA [7] vs BEGU Irina-Camelia ROU
RUS Arantxa NED vs BUZARNESCU Mihaela ROU
COLLINS Danielle USA vs 王曦雨 WANG Xiyu CHN (Q)
QUALIFIER (Q) vs KERBER Angelique GER [26]
RYBAKINA Elena KAZ [21] vs JACQUEMOT Elsa FRA (W)
日比野菜绪 HIBINO Nao JPN vs STOJANOVIC Nina SRB
VESNINA Elena RUS vs QUALIFIER (Q)
QUALIFIER (Q) vs KVITOVA Petra CZE [11]
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AZARENKA Victoria BLR [15] vs KUZNETSOVA Svetlana RUS
TAUSON Clara DEN vs BADOSA Paula ESP
FERNANDEZ Leylah CAN vs POTAPOVA Anastasia RUS
DODIN Oceane FRA (W) vs KEYS Madison USA [23]
PAVLYUCHENKOVA Anastasia RUS [31] vs MCHALE Christina USA
KOZLOVA Kateryna UKR vs TOMLJANOVIC Ajla AUS
PARRY Diane FRA (W) vs SASNOVICH Aliaksandra BLR
QUALIFIER (Q) vs SABALENKA Aryna BLR [3]
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ANDREESCU Bianca CAN [6] vs ZIDANSEK Tamara SLO
BRENGLE Madison USA vs QUALIFIER (Q)
BOUZKOVA Marie CZE vs SINIAKOVA Katerina CZE
ANISIMOVA Amanda USA vs KUDERMETOVA Veronika RUS [29]
KONTA Johanna GBR [19] vs CIRSTEA Sorana ROU
VAN UYTVANCK Alison BEL vs TREVISAN Martina ITA
KASATKINA Daria RUS vs 土居美咲 DOI Misaki JPN
PODOROSKA Nadia ARG vs BENCIC Belinda SUI [10]
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BERTENS Kiki NED [16] vs HERCOG Polona SLO
SIEGEMUND Laura GER vs GARCIA Caroline FRA
CORNET Alize FRA vs TAN Harmony FRA (W)
KANEPI Kaia EST vs VONDROUSOVA Marketa CZE [20]
RISKE Alison USA [27] vs DAVIS Lauren USA
BUREL Clara FRA (W) vs KOVINIC Danka MNE
QUALIFIER (Q) vs BOGDAN Ana ROU
TIG Patricia Maria ROU vs 大坂直美 OSAKA Naomi JPN [2]