单打96签的迈阿密大赛，各种子均首轮轮空。亚洲球员列种子的有女单的第二种子
大坂直美、21种子Rybakina、26种子Putintseva。男单则有28种子锦织圭、32种子
Bublik。
首轮男女单共有女四男三获得晋级。
[女单]
DIYAS, Zarina def. WILLIAMS, Venus 6-2 7-6
王蔷 def. BOLSOVA, Aliona 6-1 3-6 6-3
WC-王欣瑜 def. PETERSON, Rebecca 6-2 6-2
郑赛赛 def. FERRO, Fiona 2-6 6-4 6-3
OSTAPENKO, Jelena def. WC-王曦雨 6-4 6-7 6-1
ZARAZUA, Renata def. 日比野菜绪 6-4 4-6 6-1
MARTINCOVA, Tereza def. SHVEDOVA, Yaroslava 6-4 6-2
PETKOVIC, Andrea def. 张帅 7-5 6-1
[男单]
卢彦勋 def. QUERREY, Sam 6-3 6-4
内山靖崇 def. CARUSO, Salvatore 6-3 6-4
KUKUSHKIN, Mikhail def. DRAPER, Jack 7-5 0-0 Ret'd
NORRIE, Cameron def. 西冈良仁 6-1 3-6 7-5
Q-KOKKINAKIS, Thanasi def. Q-望月慎太郎 MOCHIZUKI, Shintaro 6-3 6-3
IVASHKA, Ilya def. 权纯雨 7-6 6-7 7-6