[问题] 乳房切片报告请教

楼主: luciferwing (残念)   2024-08-24 15:40:47
从健保快译通得到的乳房切片报告
看起来确定是乳癌了
想请教是否看得出哪种类型的乳癌/几期以及是否扩散?
感谢各位
Breast, right, 10 o'clock position/3 cm from nipple, core needle biopsy, ductal carcinoma in situ with invasions (invasive carcinomas and mucinous carcinoma)The specimen submitted consists of five tissue fragments measuring up to 1.7 x 0.1 x 0.1 cm in size, fixed in formalin. Grossly, they are gray and cordlike. All for section.Histologic type of right breast (10'/3) tumor: Mixed invasive carcinomas and mucinous carcinoma, some foci Histologic grade: Grade 1 (provisional in biopsy specimen) Tubule and
gland formation: < 10% (score: 3) Nuclear pleomorphism: Moderate (score: 1) Mitotic count: < 7/10 HPF (score: 1) Total score: 5 Histologic feature: Extensive spreading of ductal carcinoma in situ with some foci of invasions presenting infiltrative nests, strands and cords set in the sclerotic and desmoplastic stroma; presence of mucinous carcinoma Ductal carcinoma in situ (DCIS): Present Microcalcifications: Present in DCIS Peritumoral lymphovascular invasion: Not present in this small biopsy Perineural
invasion: Not present in this small biopsy Immunohistochemical stains (for invasions): p63: Loss of myoepithelial rimming Estrogen receptor (ER): < 1% Progesterone receptor (PR): < 1% HER2/neu protein: Positive, score 3+ Ki67 proliferation index: 5%
作者: aka79019 (阿卡)   2024-08-24 20:27:00
切片报告没办法看出是第几期,肿瘤大小跟是否扩散才是判断期别的依据,但这个要靠影像检查才能知道
楼主: luciferwing (残念)   2024-08-25 09:24:00
好的了解 感谢回复
作者: Euglena (婆娑之洋黑心之岛)   2024-08-25 19:50:00
分化度很低的乳癌,或是预后很好的粘液性乳癌;分期从切片看不出来。
作者: fafagood (柯基大神)   2024-08-26 00:48:00
看起来是黏液性的导管癌DCIS,一般来说属于预后较好的种类,但仍需要进一步检查,需要注意的是ER/PR受体阴性而HER2阳性反应,需跟主治医师讨论是否需要使用标靶药物
楼主: luciferwing (残念)   2024-08-26 16:28:00
好的~感谢楼上两位的回复
作者: eric15234 (布卡)   2024-09-09 16:23:00
这就是Her2 阳性的类型吧

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